The present work focuses on a theoretical/bibliographical discussion that will investigate the academic production of articles centered on teaching practices guided by an anti-racist education and on the implications of these actions in the school as a public institution for the formation of social subjects. The objective is to amalgamate in the work, from the analysis of the selected scientific productions, the educational potentialities and obstacles faced in the school. It is understood that such works can reverberate in the awareness of teachers and encourage anti-racist practices from the school, which is invested with greater importance when we are faced with a Brazilian society marked by the existence and perpetuity of structural racism. Therefore, when researching anti-racist educational practices and the school as a school institution, inserted in a contemporary social context, an anti-racist potential is evident from the social reproduction in the dialogue between the historical structure and current contextual practices. Moreover, obstacles are found when the historical dimension is erased from the contemporary system of practices.

El presente trabajo se centra en una discusión teórico/bibliográfica que investigará la producción académica de artículos centrados en las prácticas docentes orientadas por una educación antirracista y en las implicaciones de estas acciones en la escuela como institución pública para la formación de sujetos sociales. El objetivo es amalgamar en el trabajo, a partir del análisis de las producciones científicas seleccionadas, las potencialidades educativas y los obstáculos enfrentados en la escuela. Se entiende que tales obras pueden repercutir en la conciencia de los docentes y fomentar prácticas antirracistas desde la escuela, lo que adquiere mayor importancia cuando nos enfrentamos a una sociedad brasileña marcada por la existencia y perpetuidad del racismo estructural. Por lo tanto, al investigar las prácticas educativas antirracistas y la escuela como institución escolar, inserta en un contexto social contemporáneo, se evidencia un potencial antirracista desde la reproducción social en el diálogo entre la estructura histórica y las prácticas contextuales actuales. Además, se encuentran obstáculos cuando se borra la dimensión histórica del sistema de prácticas contemporáneo.

O presente trabalho tem como foco uma discussão de cunho teórico/bibliográfico que vai investigar a produção acadêmica de artigos com foco em práticas docentes pautadas por uma educação antirracista e nas implicações dessas ações na escola como instituição pública de formação dos sujeitos sociais. A expectativa é de amalgamar no trabalho, minimamente, as possíveis potencialidades educativas e obstáculos enfrentados na escola e que tenham sido abordados por trabalhos publicados em uma importante plataforma digital de divulgação de pesquisas acadêmicas. Entendemos que tais trabalhos podem reverberar na sensibilização de docentes e fomentar práticas antirracistas no chão da escola, o que se investe de uma maior importância ao nos deparar com uma sociedade brasileira marcada pela existência e perenidade do racismo estrutural. Diante disso, ao pesquisar práticas educativas antirracistas e a escola como instituição escolar, inserida em uma conjuntura social contemporânea.

Abstract Overview and Aims: Sentinel lymph node (SLN) biopsy in endometrial cancer has emerged as an alternative to systematic lymphadenectomy, with cervical indocyanin green injection being the preferred method. Study Design, Population and Methods: A prospective cohort study to assess the feasibility of SLN mapping in EC using ICG and near-infrared (NIR) fluorescence is ongoing at the authors’ Gynaecological Oncology Unit, in a Portuguese level III care hospital. The authors conducted a descriptive analysis of the clinicopathologic characteristics and discuss the process of implementing a novel technique. Results: A minimum number of 20 patients with EC of all histologies and grades recruited until publication was established. Of all 20 patients, 12 (12/20; 60.0%) had a total laparoscopic hysterectomy plus bilateral salpingo-oophorectomy (TLH/BSO) and SLN biopsy alone, and the remaining 8 patients underwent full retroperitoneal staging (8/20; 40.0%). At least 1 SLN was detected in all patients (20/20; 100%), bilaterally in 14 (14/20; 70%) and unilaterally in 6 (6/20; 30%). In 1 case, a third SLN was identified amongst presacral nodes. No isolated para-aortic SLNs were detected. The median number of SLNs removed per patient was 2.3 (range 1-3). Out of the 20 patients, 2 (2/20; 10%) had lymph node metastases and in both cases bilateral detection of SLN did not occur. The median operative time was 240 minutes, with total SLN mapping time of approximately 40 minutes per side. Median operative time was lower among patients undergoing an SLN mapping only, compared with patients undergoing a full lymphadenectomy (219min vs 280min). No cases of ICG injection-related complications occurred. Ultrastaging of sentinel lymph nodes was performed in all cases. Conclusions: This is the first published series of laparoscopic sentinel lymph node biopsy using ICG and NIR fluorescence in endometrial cancer, conducted in a Portuguese hospital.

Resumo Introdução e Objetivos: A biópsia de gânglio sentinela (BGS) no carcinoma do endométrio surgiu como alternativa à linfadenectomia sistemática, privilegiando-se a injeção intracervical de verde de indocianina. Métodos: Foi realizado um estudo coorte prospetivo com o intuito de avaliar a reprodutibilidade da BGS com verde de indocianina no carcinoma do endométrio, num Hospital Português de nível III. Procedeu-se à análise descritiva das caraterísticas clinico-patológicas da população estudada e discussão do processo de implementação da nova técnica. Resultados: Estabeleceu-se um mínimo de 20 doentes com carcinoma do endométrio até publicação, incluindo todos os graus e tipos histológicos. Entre as 20 doentes recrutadas, 12 (12/20; 60%) foram submetidas a histerectomia total e anexectomia bilateral (HTL/AB) e BGS e as 8 restantes a estadiamento retroperitoneal completo (8/20; 40%). Foi detetado pelo menos 1 gânglio sentinela (GS) em todos os casos (20/20; 100%), bilateralmente em 14 (14/20; 70%) e unilateralmente em 6 (6/20; 30%). Um terceiro GS sagrado foi identificado num caso. Não se identificaram GS para-aórticos. O número médio de GS removidos em cada doente foi 2.3 (intervalo 1-3). Entre as 20 doentes, 2 (2/20; 10%) apresentaram metastização ganglionar e em ambos os casos não foi possível identificar bilateralmente o GS. O tempo operatório médio foi 240 minutos e o tempo dedicado ao mapeamento ganglionar 40 minutos, unilateralmente. O tempo operatório médio foi inferior nas doentes submetidas a BGS, comparativamente à linfadenectomia sistemática (219 minutos vs 280 minutos). Não houve complicações associadas à injeção do marcador. Foi realizado ultraestadiamento em todos os casos. Conclusões: A presente publicação é a primeira série de casos portuguesa reportada de biópsia de gânglio sentinela com verde de indocianina, por via laparoscópica no carcinoma do endométrio.

ABSTRACT: Using portable blood glucose meters (PBGMs) to measure blood glucose (BG) concentration is a common procedure in veterinary practice. Our objective was to evaluate the analytical and clinical accuracy of a human PBGM (Accu-Chek Performa®), (AC) and a veterinary PBGM (GlucoCalea®), (GC) in feline patients. Central venous blood samples were collected from 48 cats at a Brazilian Veterinary teaching hospital. Two devices from each model were used and compared to a reference method (RM). Analytical accuracy was assessed according to ISO 15197:2013 requirements for human PBGMs. Data were compared using Wilcoxon’s nonparametric test and represented by Bland-Altman plots. Hematocrit’s effect on BG measurements was evaluated by the Spearman correlation coefficient. Clinical accuracy was determined using error grid analysis (EGA). Values of BG were significantly higher in all PBGMs compared to the RM. Although ISO’s analytical accuracy requirements could not be met by any of the devices, AC meters were more accurate than GC meters. All AC measurements - but not GC ones - were within zones A and B of the EGA, meeting ISO requirements for clinical accuracy. Significant hematocrit interference was observed in all devices. Therefore, AC showed greater accuracy compared to GC using feline whole blood samples.

RESUMO: O uso de glicosímetros portáteis (GPs) para aferição da glicemia é um procedimento comum na rotina clínica veterinária. O objetivo deste trabalho é avaliar a acurácia analítica e clínica de um GP humano (Accu-Chek Performa®), (AC) e um GP veterinário (GlucoCalea®), (GC) em gatos. Amostras de sangue venoso central foram coletadas de 48 gatos atendidos em um hospital veterinário-escola no Brasil. Foram utilizados dois GPs de cada modelo e comparados a um método de referência (MR). A acurácia analítica foi avaliada de acordo com os requisitos estipulados pela ISO 15197:2013 para GPs de uso humano. Os dados foram comparados pelo teste não-paramétrico de Wilcoxon e representados em gráficos de Bland-Altman. O efeito do hematócrito sobre os valores de glicemia foi avaliado pelo coeficiente de correlação de Spearman. A acurácia clínica foi avaliada pela análise da grade de erros (AGE). Em comparação com o MR, os valores de glicemia foram maiores em todos os GPs avaliados. Nenhum deles atendeu aos requisitos da ISO quanto à acurácia analítica, mas o AC mostrou-se mais acurado que o GC. Todos os valores de glicemia obtidos pelos GPs humanos - mas não pelos GPs veterinários - estiveram dentro das zonas A e B da AGE, demonstrando acurácia clínica de acordo com as exigências da ISO. A interferência do hematócrito da amostra mostrou-se significativa em todos os aparelhos testados. Portanto, o AC apresentou maior acurácia quando comparado ao GC em amostras de sangue total em felinos.

Abstract Introduction: Secondary Aortoesophageal fistula (AEF) is a rare but serious complication following thoracic endovascular aneurysm repair (TEVAR), which may lead to fatal outcomes. Case report: We present the case of a 62-year-old patient developing a secondary AEF one-month after TEVAR. The patient was managed in a staged approach: first, an oesophagus defunctionalisation by cervical oesophagus stapling, followed by drainage gastrostomy and creation of a feeding jejunostomy. Two-weeks later, the patient underwent stent graft explantation, extensive debridement, in situ aortic reconstruction with interposition of a silver and Triclosan impregnated Dacron graft, esophagectomy, eosophagogastrostomy and intercostal muscle flap plasty. After 4 years of follow-up, the patient remains clinically well and free from recurrence. Conclusion: The diagnosis of AEF requires a high index of suspicion. A prompt and aggressive multidisciplinary approach is necessary to obtain long-term survival and freedom from recurrence.

ABSTRACT Earth construction is an ancestral technique, which in recent years has attracted a lot of attention due to its sustainability, ease of execution and low-cost production. Compacted earth blocks (CEBs) are a current and modern construction technique based on ancient adobe and rammed earth construction techniques. On the other hand, phase change materials (PCM) have been successfully applied in different building materials, due to their ability to regulate the temperature inside buildings through their thermal storage capacity. In this way, the combination of compacted earth blocks and phase change materials allows for a constructive solution with all the advantages associated with earth construction, but also with a beneficial impact on the energy efficiency of buildings. Currently, there are several studies developed in earth construction and in materials with PCM incorporation, however the combination of these two techniques is still an underdeveloped area with high potential and research needs. In this research, different compositions of CEBs with direct incorporation of non-encapsulated PCM were developed and evaluated in the fresh and hardened state. The developed compositions were added with 25%, 50% and 75% of PCM in relation to the Portland cement content used to stabilize the BTCs. It was possible to conclude that the incorporation of PCM in BTCs can be performed successfully, with the incorporation 25% of PCM and 10% of Portland cement presenting a satisfactory performance from the point of view of physical, mechanical behavior and durability.

RESUMO A construção em terra é uma técnica ancestral, que nos últimos anos tem atraído muita atenção devido à sua sustentabilidade, facilidade de execução e baixo custo produtivo. Os blocos de terra compactada (BTCs) são uma técnica de construção moderna e atual, baseada nas antigas técnicas construtivas de adobe e taipa. Por sua vez, os materiais de mudança de fase (PCM) têm vindo a ser aplicados com sucesso em diferentes materiais de construção, devido à sua capacidade de regulação da temperatura no interior de edifícios por meio da sua capacidade de armazenamento térmico. Desta forma, a associação dos blocos de terra compactada e dos materiais de mudança de fase, permite obter uma solução construtiva com todas as vantagens associadas à construção em terra, mas também com impacto benéfico na eficiência energética dos edifícios. Atualmente, são várias as investigações desenvolvidas em construção em terra e em materiais aditivados com PCM, no entanto a combinação destas duas técnicas é ainda uma área subdesenvolvida, com elevado potencial e grande necessidade de investigação. Nesta investigação foram desenvolvidos e caracterizados BTCs com incorporação direta de PCM não encapsulado, tendo sido avaliadas diferentes composições no estado fresco e endurecido. As composições desenvolvidas foram aditivadas com 25%, 50% e 75% de PCM em relação à quantidade de cimento utilizada para a estabilização dos BTCs. Foi possível concluir que a incorporação do PCM em BTCs pode ser realizada com sucesso, apresentando o teor de incorporação de 25% de PCM e 10% de cimento Portland um desempenho satisfatório sob o ponto de vista do comportamento físico, mecânico e de durabilidade.

Abstract Overview and Aims: The incidence of women in their antenatal and postpartum period who require hospitalization in the Intensive Care Unit (ICU), has been repeatedly used as a marker of quality for health services. In Portugal there are currently few studies that report on obstetric complications and the need for a more multidisciplinary approach after admission to an ICU. The main objective of this study is to determine the probability for intensive care admission need of this Centre’s obstetric population. The secondary objectives are to characterize the obstetric population, it’s risk factors and outcomes. Study design: Descriptive and retrospective study Population: All women hospitalized at an ICU in our Centre, during pregnancy or in the 42 days postpartum, in 2013 and 2020. Methods: We assessed the electronic and physical records of our eligible population and analyzed relevant variables such as maternal age, body mass index, gestational age at admission, and delivery route. Neonatal variables, such as weight at delivery, apgar scores and adverse neonatal outcomes were also evaluated. Results: During the study period, 41 women required hospitalization in ICU, out of a total of 14 688 births. The most frequent diagnosis at admission were hypertensive disorders and postpartum hemorrhage. Mean age was 30.4 years. Most admissions were in the postpartum period (97,6%). We observed two maternal deaths and one fetal death. Conclusions: The admission rate to the ICU was 2.8 per 1000 births. Most admissions occurred in the postpartum period (97.6%), with the most common reasons being hypertensive disorders (56.1%) and postpartum hemorrhage (31.7%). The maternal mortality rate was 0.14 per 1000 births. These results were similar to those found in other international and national studies.

ABSTRACT Purpose: To evaluate efficacy of urorectal fistula (URF) repair using different approaches and the clinical factor determinant of success, and also the morbidity associated to the procedure and health-related quality of life (HRQoL) in male survivors of pelvic malignancies. Material and Methods: Retrospective evaluation of 39 patients with URF primarily intervened in three institutions using different surgical approaches. Success was defined as effective fistula closure. Variables evaluated included demographics, previous treatments, surgical approach, ancillary surgeries, complications and HRQoL by using a standardized non-validated specific questionnaire. Median follow-up from surgery to interview was 55 months (interquartile range 49, range 4-112). Factors determinant of success were investigated using logistic regression. Safety of the procedure was evaluated by Clavien-Dindo scale. Deterioration of continence and erectile function and other HRQoL issues were evaluated. Results: Prostate cancer treatment was the predominant etiology. The success rate for fistula repair was 89.5%. The surgical approach was not related to failed repair (p=0.35) or complications (p=0.29). Factors associated with failure were complications (p=0.025), radiotherapy (p=0.03), fistula location (p=0.04) and fistula size (p=0.007). Multivariate analysis revealed fistula size was the only independent determinant of failure (OR 6.904, 1.01-47.75). Complications occurred in 46.2% and severe complications in 12.8%. The mortality related to the procedure was 2.6%. Urinary incontinence was present before repair in 26.3% and erectile dysfunction in 89.5%. Fistula repair caused de novo urinary incontinence in 7.9% and deterioration of erectile status in 44.7%. Globally 79% were satisfied after repair and only 7.9% rated HRQoL as unhappy. Trans-sphincteric approach was related to less deterioration of erectile function (p=0.003), and higher perceived satisfaction in QoL (p=0.04). Conclusions: The surgical approach elected to correct URF is not determinant of success nor of complications. Fistula size appears as independent determinant for failure. Transsphincteric approach could be advantageous over other procedures regarding HRQoL issues.

RESUMO: Objetivou-se com este estudo avaliar os efeitos do tratamento de cães com erliquiose monocítica canina (EMC) com cloridrato de doxiciclina associada ou não à prednisolona sobre o perfil hematológico e de proteínas séricas. Foram selecionados, na Clínica Médica de Pequenos Animais do Hospital Veterinário da Universidade Federal de Campina Grande (UFCG), 10 cães com EMC. O diagnóstico foi obtido através de exame clínico, hemograma e teste de imunoensaio imunocromatográfico (com anticorpos anti Ehrlichia canis). As amostras foram distribuídas aleatoriamente em dois grupos experimentais, com cinco animais cada (n=5), denominados GD e GDP. O grupo GD foi tratado com doxiciclina (5 mg/kg, VO, BID durante 28 dias) e o grupo GDP, tratado com doxiciclina na mesma dose e duração e prednisolona (2 mg/kg, VO, BID, durante 5 dias). Durante o período de tratamento, foram realizadas quatro coletas de sangue; uma coleta basal (M0), uma com 10 dias (M10), uma aos 21 dias (M21) e outra ao final do tratamento (M28). Dessas amostras foram realizados eritrograma, leucograma, plaquetograma e proteinograma (dosagem de proteínas totais, pré-albumina, albumina, α-1 globulina, α-2 globulina, ß-globulina, ɣ-globulina e proteína C-reativa) no Laboratório de Patologia Clínica do Hospital Veterinário da UFCG. Os resultados que apresentaram distribuição normal foram submetidos ao teste de Tukey (P<0,05). Ao comparar os tratamentos GD e GDP, observou-se que os dois promoveram resposta discreta e semelhante dos parâmetros hematológicos nos diferentes momentos. Os resultados obtidos permitem concluir que ambos os protocolos terapêuticos resultaram em melhora clínica e dos parâmetros hematológicos e do proteinograma. Porém, o uso da prednisolona na dose empregada durante os primeiros cinco dias de tratamento não demonstrou efeitos mais benéficos do que a administração isolada da doxiciclina.

ABSTRACT: The objective of the present study was to assess the treatment of dogs with ehrlichiosis (tropical canine pancytopenia (TCP)) with doxycycline hydrochloride associated or not with prednisolone on the hematological profile and serum proteins. Ten dogs with TCP were selected in the Small Animal Medical Clinic Veterinary Hospital, Federal University of Campina Grande-UFCG-PB, Brazil. The diagnosis was obtained by clinical examination, hemogram and immunochromatographic test (with anti Ehrlichia canis antibodies). Samples were distributed randomly in two experimental groups of five animals each (n = 5), named GD and GDP. The GD group was treated with doxycycline (5 mg/kg, VO, BID for 28 days) and the GDP group was treated with doxycycline at the same dose and duration and prednisolone (2 mg/kg, VO, BID, for five days). Four blood collections were made during the treatment period: a base collection (M0), one at 10 days (M10), a second at 21 days (M21) and another at the end of the treatment (M28). These samples were used for the tests erythrogram, leucogram, plateletgram and proteinogram (dose of total proteins, pre-albumin, albumin, albumin, α-1 globulin, α-2 globulin, ß-globulin, ɣ-globulin and C- reactive protein) in the Clinical Pathology Laboratory, Veterinary Hospital-UFCG-PB. Results, that presented normal distribution, was submitted to the Tukey test (P<0.05). Comparison of treatments GD and GDP showed that both promoted discreet and similar response in the hematological parameters at different times. Results obtained allowed the conclusion that both therapeutic protocols resulted in clinical, hematological parameter and proteinogram improvement, but the use of prednisolone at the dose administered during the first five days of treatment did not show more beneficial effects than isolated administration of doxycycline.

Neste artigo, abordamos a implicação e o papel dos verbos modais/páthicos na construção das promessas e sua relação com as modalidades superegoicas da adolescência na atualidade. As promessas, no sentido em que as tomamos aqui, são entendidas como uma ação de comprometimento realizada via linguagem, podendo ser usadas como dispositivos efetivos para o entendimento das modalizações superegoicas do adolescente. O supereu, por sua vez, é percebido como o principal (des)organizador da modalização pulsional representada pelos verbos. Partimos do princípio de que o verbo carreia a pulsão e também monta o foro intrapsíquico humano, sendo assim, entender o modo como os adolescentes se referem aos verbos pode auxiliar a entender a respeito dos conflitos morais e pulsionais do adolescente construído frente à cultura atual.

This article addresses the implication and role of modal/pathic verbs in the construction of promises and their relationship with the superego modalities of adolescence today. Promises are here understood as a commitment made via language and they may be used as effective devices to understand superego modalizations of adolescents. The super-ego, in turn, is perceived as the main (dis)organizer of the drive modalization represented by the verbs. We assume that the verb carries the drive and also assembles the human intrapsychic forum. Thus, to understand how adolescents refer to verbs may help to understand their conflicts with moral and drive which come up in the face of our current culture.

En este artículo, abordamos la implicación y el papel de los verbos modales/pháticos en la construcción de promesas y su relación con las modalidades del superego de la adolescencia actual. Las promesas, en el sentido abordado aquí, se entienden como una acción de compromiso realizada a través del lenguaje y se pueden usar como dispositivos efectivos para la comprensión de las modalizaciones del superego adolescente. El superyó, por su parte, se percibe como el principal (des)organizador de la modalización pulsional representada por los verbos. Partimos del principio de que el verbo lleva la pulsión y también ensambla el foro intrapsíquico humano, por lo cual, comprender la forma en la que los adolescentes se refieren a los verbos, puede ayudar a entender sobre los conflictos morales y pulsionales del adolescente construido frente a la cultura actual.

Dans cet article, nous abordons l’implication et le rôle des verbes modaux/pathiques dans la construction des promesses et leur rapport avec les modalités du surmoi de l’adolescence aujourd’hui. Les promesses, dans le sens où nous les prenons ici, sont comprises comme une action de compromis effectuée par le langage et elles peuvent être utilisées comme des dispositifs efficaces pour comprendre les modalisations du surmoi adolescent. Le surmoi, à son tour, est perçu comme le (dés)organisateur principal de la modalisation pulsionnelle représentée par les verbes. Nous supposons que le verbe porte la pulsion et assemble également le forum intrapsychique humain. Comprendre comment les adolescents se réfèrent aux verbes peut aider à comprendre les conflits moraux et pulsionnels des adolescents construits face à la culture actuelle.

RESUMO: A caracterização clínica-epidemiológica de doenças auxilia no direcionamento do diagnóstico. O objetivo deste trabalho foi descrever aspectos epidemiológicos, clínicos e laboratoriais de uma série de casos de hiperadrenocorticismo (HAC) canino. Foram avaliados 115 prontuários de cães diagnosticados pelo teste de supressão por baixa dose de dexametasona e/ou teste de estimulação com ACTH. Os casos de HAC ACTH-dependentes representaram 81,3% da população, e 18,7% foram ACTH-independentes. As fêmeas foram mais acometidas, representando 69,3% dos casos. A média de idade foi 10,3 ± 2,5 anos e 64,9% eram gonadectomizados. A maioria dos cães foi de porte pequeno, de até 10 kg (73,9%). As raças mais frequentes foram Poodle (27%), Dachshund (17,4%) e Yorkshire (10,4%). As manifestações clínicas mais relatadas foram polifagia (86%), polidipsia (82,6%), poliúria (80%), abdome pendular (82,6%), atrofia cutânea (79,1%), fraqueza muscular (78,3%) e dispneia (74,8%). Entretanto, eventualmente sinais clínicos pouco associados ao HAC se manifestaram de forma mais importante que os sinais clássicos da doença. O hemograma revelou neutrofilia (66%), eosinopenia (58,3%) e linfopenia (42,6%) como principais alterações hematológicas. Na bioquímica sérica foi observado aumento de fosfatase alcalina (81,74% dos casos), aumento da atividade da ALT (62,6%), hipercolesterolemia (66%) e hipertrigliceridemia (54,7%). A urinálise revelou hipostenúria em 14,9% e isostenúria em 13,5%; além de proteinúria em 50% dos casos. A ecografia abdominal evidenciou hiperplasia bilateral de adrenal (92,2%) com assimetria de adrenais em 20,8% dos casos, além de hepatomegalia (80,9%), lama biliar (67,8%) e hiperecogenicidade hepática (47,8%). Concluiu-se que fêmeas castradas de pequeno porte, principalmente das raças Poodles e Dachshunds, apresentaram maior frequência na população estudada e que as principais alterações observadas clínicas e nos exames complementares foram polifagia, poliúria, polidipsia, aumento abdominal, hiperplasia da adrenal, aumento de fosfatase alcalina e hiperlipidemia. Estes resultados corroboram para melhor caracterização da doença no Brasil. Este estudo concluiu que a população estudada se assemelha ao perfil populacional de cães com HAC descrito em estudos Europeus e Norte Americanos de forma que o perfil dos casos ao redor do globo parece similar.

ABSTRACT: Diseases’ clinical-epidemiological characterization assists in directing the diagnosis. The objective of this study was to describe epidemiological, clinical and laboratorial aspects of a case series of canine hyperadrenocorticism (HAC). One-hundred fifteen records of dogs diagnosed by the low dose dexamethasone suppression test and/or ACTH stimulation test were evaluated. Of the cases, 81.3% were HAC ACTH-dependent and 18.7% HAC ACTH-independent. Females were more affected, representing 69.3% of the cases. The mean age was 10.3±2.5 years and 64.9% were gonadectomized. Most of the patients were small size dogs, weighting less than 10kg (73.9%). The most frequent breeds were: Poodle (27%), Dachshund (17.4%), and Yorkshire Terrier (10.4%). The most frequent clinical manifestations were polyphagia (86%), polydipsia (82.6%), polyuria (80%), abdominal enlargement (82.6%), thin skin (79.1%), muscular weakness (78.3%) and panting (74.8%). However, eventually unusual HAC-associated signs would be present in some dogs in a more important way compared with the classic disease´s clinical signs. The CBC showed neutrophilia (66%), eosinopenia (58.3%) and lymphopenia (42.6%) as main hematological abnormalities. The most common findings in serum biochemistry were increased alkaline phosphatase activity (81.74%), increased ALT activity (62.6%), hypercholesterolemia (66%) and hypertriglyceridemia (54.7%). Urinalysis revealed hyposthenuria in 14.9% and isostenuria in 13.5%; besides proteinuria in 50% of the cases. Abdominal ultrasound showed bilateral adrenal hyperplasia (92.2%) with adrenal asymmetry in 20.8% of the cases, in addition to hepatomegaly (80.9%), biliary sludge (67.8%) and hepatic hyperechogenicity (47.8%). It was concluded that small size gonadectomized female dogs, mainly Poodles and Dachshunds, presented higher frequency in the population studied, and that the main changes observed in clinical and complementary tests were polyphagia, polyuria, polydipsia, abdominal enlargement, adrenal hyperplasia, increased phosphatase alkaline and hyperlipidemia. These results corroborated to a better disease characterization at Brazil. This work concluded that the population studied resembles the profile describe in European and North American epidemiologic studies, and that the HAC dog´s clinical picture looks similar worldwide.

Resumo Objetivo Comparar a abordagem laparoscópica com a laparotômica no estadiamento cirúrgico do carcinoma do endométrio. Métodos Avaliação retrospectiva de uma coorte de mulheres com diagnóstico préoperatório de cancro do endométrio submetida a estadiamento cirúrgico. As principais variáveis do estudo foram: morbilidade e mortalidade, tempo de internamento hospitalar, eventos adversos peri-operatórios e taxa de recorrência. A análise dos dados foi realizada com o programa SPSS v25 (IBM Corp, Armonk, NY, EUA), para as variáveis categóricas utilizou-se o teste do Qui-quadrado e o teste de Fisher, e para as variáveis contínuas o teste t de Student. Resultados A amostra foi constituída por 162 doentes. 138 pacientes preencheram os critérios de inclusão, 41 das quais foram submetidas a estadiamento por laparoscopia e 97 por laparotomia. As conversões de laparoscopia para laparotomia ocorreram em 2 doentes (4,9%) e foram secundárias a dificuldades técnicas e má exposição. A laparoscopia teve menos eventos adversos pós-operatórios quando comparada à laparotomia (7,3% versus 23,7%, respectivamente; p = 0,005), mas taxas semelhantes de complicações intraoperatórias, apesar do tempo operatório significativamente maior (mediana 175 a 130 minutos, respetivamente; p < 0,001). A permanência hospitalar foi significativamente menor na abordagem laparoscópica (mediana de 3 versus 7 dias, respectivamente; p < 0,001). Não houve diferenças nas taxas de recorrência ou mortalidade. Conclusão O estadiamento cirúrgico laparoscópico para carcinoma do endométrio é exequível e seguro. As doentes apresentam uma menor taxa de complicações pósoperatórias e tempo de internamento mais curto quando comparados aos da abordagem por laparotomia.

Abstract Objective To compare laparoscopy with laparotomy for surgical staging of endometrial cancer. Methods A cohort of women with preoperative diagnosis of endometrial cancer who underwent surgical staging was retrospectively evaluated. The main study end points were: morbidity and mortality, hospital length of stay, perioperative adverse events and recurrence rate. Data analysis was performed with the software SPSS v25 (IBM Corp., Armonk, NY, USA), categorical variables using a Chi-square and Fisher test, and continuous variables using the Student t-test. Results Atotal of 162 patientswere analyzed. 138 patientsmet the inclusion criteria, 41of whom underwent staging by laparoscopy and 97 by laparotomy. Conversions from laparoscopy to laparotomy happened in 2 patients (4.9%) and were secondary to technical difficulties and poor exposure. Laparoscopy had fewer postoperative adverse events when compared with laparotomy (7.3% vs 23.7%, respectively; p = 0.005), but similar rates of intraoperative complications, despite having a significantly longer operative time (median, 175 vs 130 minutes, respectively; p < 0.001). Hospital stay was significantly lower in laparoscopy versus laparotomy patients (median, 3 vs 7 days, respectively; p < 0.001). No difference in recurrence or mortality rates were observed. Conclusion Laparoscopic surgical staging for endometrial cancer is feasible and safe. Patients have lower postoperative complication rates and shorter hospital stays when compared with the approach by laparotomy.

RESUMO O material CuCr2O4 foi sintetizado pela reação de combustão em solução e tratado termicamente na faixa de 600 à 1100oC, afim de verificar a evolução das fases. O composto foi carcterizado estrutural e morfologicamente por meio das técnicas de Difração de Raios X (DRX), refinamentos pelo método de Rietveld, Microscopia Eletrônica de Varredura com canhão de elétrons por emissão de campo (MEV-FEG) e espectroscopia na região do Infravermelho com transformada de Fourrier. O comportamento da sinterização do material foi analisado por meio da dilatometria. Por meio dos padrões da difração de raios X (DRX) observou-se a formação da fase pura da Cromita de Cobre na faixa de 700-1000°C, a qual é corroborada pelo Refinamento Rietveld. Quanto a morfologia, as fases puras da cromita de cobre apresentaram formas de poliedros regulares. Por meio da dilatometria observou-se que o material apresentou uma expansão seguida de retração associada a mudança estrutural do material.

ABSTRACT CuCr2O4 material was subjected to solution combustion synthesis and heat-treated in the range of 600 to 1100oC in order to analyze its phase evolution. The structure and morphology of the composite were characterized by X-ray diffraction (XRD), Rietveld refinement, field emission gun scanning electron microscopy (FEG-SEM) and Fourier transform infrared spectroscopy (FTIR), while its sintering behavior was analyzed by dilatometry. The XRD patterns revealed the formation of pure phase copper chromite in the range of 700-1000°C, which was confirmed by Rietveld refinement. This pure phase copper chromite exhibited a regular polyhedral shaped morphology. The dilatometric analysis indicated that the composite underwent thermal expansion followed by shrinkage, which were attributed to structural changes in the material.

ABSTRACT The purpose of this study is to develop data mining models to predict restrained shrinkage crack widths of slag mortar cementitious composites. A database published by BILIR et al. [1] was used to develop these models. As a modelling tool R environment was used to apply these data mining (DM) techniques. Several algorithms were tested and analyzed using all the combinations of the input parameters. It was concluded that using one or three input parameters the artificial neural networks (ANN) models have the best performance. Nevertheless, the best forecasting capacity was obtained with the support vector machines (SVM) model using only two input parameters. Furthermore, this model has better predictive capacity than adaptative-network-based fuzzy inference system (ANFIS) model developed by BILIR et al. [1] that uses three input parameters.

Abstract Abstract: This study defines the neostratotype of the Lower-Middle Albian Itapecuru Formation in the Parnaíba Basin, Northeast Brazil. In this sedimentary succession along the right bank of the Itapecuru River near the Itapecuru-Mirim City, Maranhão State, three lithofacies associations are recognized. The first is silty claystone with some very fine sand, micaceous, reddish color, thin laminated, showing a tabular aspect, interpreted as floodplain fines in a distal position. The second is clayey siltstone, reddish color, with ripple cross-lamination, very thin cross-laminated wacke lenses, grading to thin parallel lamination, in apparently tabular layers, interpreted as crevasse splay and distributive channels deposits in successive avulsion events. The third is fine quartz wacke, reddish to grayish color, showing grouped trough cross bedding, interpreted as channel filling deposits. These facies associations correspond to part of a fluvial depositional system, with predominantly fine-grained rocks, and small lakes in the floodplain, in an oxidizing environment and marked by seasonality. These field data, reinforced by grain size and petrographic analyses showed that, contrary to previous descriptions, the Itapecuru Formation consists mainly of mudrocks. This research also shows that the medium to coarse sandstones and conglomerates, previously included in the Itapecuru Formation, belong to the underlying Grajaú Formation.

L'objectif de ce travail est d'analyser la Boca de Ouro de Nelson Rodrigues dans les aspects de perversion et de ressentiment. La construction de l'antihéros Boca de Ouro révèle le fonctionnement d'un Super moi corrompu dans lequel il fait appel à la tyrannie comme une formation réactive pour se défendre du ressentiment d'être un enfant sans père et d'une mère qui a accouché dans un évier de salle de bal. Le concept de ressentiment est discuté à partir de la psychanalyse freudienne et de la philosophie de Nietzsche.

The purpose of this paper is to analyze Nelson Rodrigues' Boca de Ouro in aspects related to perversion and resentment. The construction of the anti-hero Boca de Ouro reveals the workings of a corrupted Super-ego, in which he appeals to tyranny as a reactive formation to defend himself from the resentment of being a fatherless child, and whose mother gave birth to him in a nightclub sink The concept of resentment is discussed based on Freudian psychoanalysis and on Nietzsche's philosophy.

Ziel dieser Arbeit ist es, das Theaterstück „Boca de Ouro” von Nelson Rodrigues in Bezug auf die Begriffe Perversion und Ressentiment zu analysieren. Die Konstruktion des Antihelden Boca de Ouro offenbart die Existenz eines korrupten Überichs, das an die Tyrannei als eine reaktive Formation appelliert, um das Ressentiment abzuwenden, ein vaterloses Kind zu sein, das im Waschbecken einer Gafieira [Tanzsalon] zur Welt kam. Das Konzept des Ressentiments wird im Licht der Freud'schen Psychoanalyse und Nietzsches Philosophie erörtert.

O objetivo deste trabalho é analisar a peça “Boca de Ouro”, de Nelson Rodrigues, nos aspectos concernentes à perversão e ao ressentimento. A construção do anti-herói Boca de Ouro revela o funcionamento de um Supereu corrompido no qual apela-se para a tirania como uma formação reativa para defender-se do ressentimento de ser um filho sem pai e de uma mãe que deu à luz em uma pia de gafieira. O conceito de ressentimento é discutido a partir da psicanálise freudiana e da filosofia de Nietzsche.

El objetivo de este trabajo es analizar la obra Boca de Oro, de Nelson Rodrigues, en lo relacionado a la perversión y al resentimiento. La construcción del antihéroe, Boca de Oro, revela el funcionamiento de un Superyó corrompido en el que se apela a la tiranía, como una formación reactiva, para defenderse del resentimiento de ser un hijo sin padre y de una madre que dio a luz en el lavabo de una discoteca. El concepto de resentimiento se discute a partir del psicoanálisis freudiano y de la filosofía de Nietzsche.